Epithelial-Mesenchymal Transition Induced by Senescent Fibroblasts
نویسندگان
چکیده
منابع مشابه
Epithelial‐to‐mesenchymal transition transcription factors in cancer‐associated fibroblasts
Beyond inducing epithelial-to-mesenchymal transcription (EMT), transcriptional factors of the Snail, ZEB and Twist families (EMT-TFs) control global plasticity programmes affecting cell stemness and fate. Literature addressing the reactivation of these factors in adult tumour cells is very extensive, as they enable cancer cell plasticity and fuel both tumour initiation and metastatic spread. In...
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Owing to this fact that most of the mortalities in cancers are as a result of metastasis, study on the involved pathways in metastasis including Epithelial to mesenchymal transition (EMT) would be so critical and important. Up to date, several extensive studies have been carried out to determine the correlation between EMT and cancer and their results have shown that the EMT plays pivotal role ...
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ژورنال
عنوان ژورنال: Cancer Microenvironment
سال: 2011
ISSN: 1875-2292,1875-2284
DOI: 10.1007/s12307-011-0069-4